Rapid Report on Rare Disease Epidemiology

A US-based top five pharmaceutical sponsor wanted to rapidly curate key evidence across specific geographies on Focal Segmental Glomerular Sclerosis (FSGS) epidemiology for identifying treatable population.

Key challenges to the completion of an evidence synthesis product included the rare nature of data, strict evidentiary requirements with expectations for accurate estimations, and client time constraints.

To meet this unique business need, a team of RWE functional experts was deployed. The team was enabled by an AI- based solution that provides evidence-based auto-sorting of records, intuitive natural language processing (NLP) captures, and collaborative document editing with annotation. Finally, practical insights from public health experts, senior HEOR analysts, and epidemiologists were considered.

The Catalyst Flex solution delivered Early identification of distinct epidemiological transitions depending on variations in geographies, report development time reduced by ~55% to 15 days, and QC time reduced by 10 hours due to zero false positive retrievals and NLP-extracted epidemiology information.

This provided brand teams and market access teams with a report 8+ weeks ahead of their commercial strategies meeting for target markets and saved them up to 75% of the cost of a standard outsourced report.