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Development of Novel Wearables and AI Capabilities to Support the Monitoring of COVID-19 Patients

March 10, 2022

As the COVID-19 pandemic developed, it soon emerged that hospital staff faced significant challenges in identifying/predicting which patients would need critical care. This became increasingly important as COVID-19 increased, stretching the capacity of ward staff to traditionally (manually) monitor patients’ vital signs, a critical element of assessing a patients clinical status. Given some patients with COVID-19 deteriorate rapidly, a key concern was to identify accurately which patients were going to deteriorate.

Aptus Clinical and AI collaboration partner Zenzium, worked closely with clinicians at The Christie and MFT to develop the ground-breaking COSMIC-19 study. This study was designed to assess the feasibility and utility of continuous vital signs monitoring and AI modelling to monitor and predict deterioration in patients admitted with COVID-19.

Wireless, wearable sensors were used to continually collect patients’ vital signs, until the patient was either discharged or admitted to ITU. Together with clinical data and observations, Zenzium is using Artificial Intelligence (AI) technology to look for predictive patterns that could alert medical staff to a patient’s deterioration or provide reassurance that a patient will continue to improve.

The COSMIC-19 study progressed from idea to first patient recruited in 4 months, with 46 patients recruited to date and AI modelling activities ongoing. The study has provided valuable insights into the feasibility and practicality of deploying such wearable technology into busy hospital wards and the potential for use in future multi-centre clinical trials. One publication has already been generated, with more to follow.

As COVID-19 moves to being an endemic infection, we are excited at the potential opportunity for the model we generated to be further developed as a clinical decision support tool. This will hopefully improve clinical outcomes and optimise the efficiency and utilisation of scarce hospital resources.

The collaborative delivery partnership that has successfully been built between Aptus Clinical, Zenzium, The Christie and MFT has secured additional funding to expand and develop these novel wearables and AI capabilities:

We are delighted to have been involved with the design and delivery of this innovative study. It felt particularly significant to be working on an exploratory COVID-19 study throughout the pandemic. We are hopeful the utilisation of patient wearables is something we can continue to develop to access more patients across Manchester and beyond. Steve McConchie, Aptus Clinical